01/By surface
each with its own count, at equal weight
Hard
1-0
S. leads 1-0 in 1 meeting on hard
Clay
4-2
S. leads 4-2 in 6 meetings on clay
Grass
Never on grass
no meeting on this surface
02/Every meeting
7 rows, newest first
| Date | Tournament | Surface | Round | Winner | Score, winner first | Ranks, S. first |
|---|---|---|---|---|---|---|
| Apr 29, 2025 | Mutua Madrid OpenMasters 1000 | clay | 3rd round | Musetti L. | 7-5, 7-6 | 18 v 11 |
| Apr 11, 2025 | Monte Carlo MastersMasters 1000 | clay | quarterfinal | Musetti L. | 1-6, 6-3, 6-4 | 8 v 16 |
| May 16, 2023 | Internazionali BNL d'ItaliaMasters 1000 | clay | 4th round | Tsitsipas S. | 7-5, 7-5 | 5 v 19 |
| Apr 22, 2023 | Barcelona OpenATP500 | clay | semifinal | Tsitsipas S. | 6-4, 5-7, 6-3 | 5 v 20 |
| May 24, 2022 | French OpenGrand Slam, best of 5 | clay | 1st round | Tsitsipas S. | 5-7, 4-6, 6-2, 6-3, 6-2 | 4 v 66 |
| May 22, 2021 | Lyon OpenATP250 | clay | semifinal | Tsitsipas S. | 4-6, 6-3, 6-0 | 5 v 88 |
| Mar 20, 2021 | Abierto MexicanoATP500 | hard | semifinal | Tsitsipas S. | 6-1, 6-3 | 5 v 120 |
A record, never a share of meetings. Main-draw singles since 2013; a meeting ended by retirement is counted with the sets that were played and marked; a walkover is listed and counted in neither column. Tsitsipas S. and Musetti L. each carry the table against every opponent faced.