01/By surface
each with its own count, at equal weight
Hard
3-0
K. leads 3-0 in 3 meetings on hard
Clay
1-0
K. leads 1-0 in 1 meeting on clay
Grass
Never on grass
no meeting on this surface
02/Every meeting
4 rows, newest first
| Date | Tournament | Surface | Round | Winner | Score, winner first | Ranks, K. first |
|---|---|---|---|---|---|---|
| Mar 13, 2019 | BNP Paribas OpenMasters 1000 | hard | 4th round | Khachanov K. | 6-4, 7-6 | 13 v 9 |
| Nov 1, 2018 | BNP Paribas MastersMasters 1000 | hard | 3rd round | Khachanov K. | 6-4, 6-7, 7-6 | 18 v 9 |
| Aug 9, 2018 | Rogers MastersMasters 1000 | hard | 3rd round | Khachanov K. | 7-6, 7-6 | 38 v 9 |
| Jun 4, 2017 | French OpenGrand Slam, best of 5 | clay | 3rd round | Khachanov K. | 7-6, 6-3, 6-7, 7-6 | 53 v 22 |
A record, never a share of meetings. Main-draw singles since 2013; a meeting ended by retirement is counted with the sets that were played and marked; a walkover is listed and counted in neither column. Khachanov K. and Isner J. each carry the table against every opponent faced.