01/By surface
each with its own count, at equal weight
Hard
4-3
Potro J.M. leads 4-3 in 7 meetings on hard
Clay
1-0
Potro J.M. leads 1-0 in 1 meeting on clay
Grass
0-1
J. leads 1-0 in 1 meeting on grass
02/Every meeting
9 rows, newest first
| Date | Tournament | Surface | Round | Winner | Score, winner first | Ranks, Potro J.M. first |
|---|---|---|---|---|---|---|
| Sep 4, 2018 | US OpenGrand Slam, best of 5 | hard | quarterfinal | Del Potro J.M. | 6-7, 6-3, 7-6, 6-2 | 3 v 11 |
| Jun 4, 2018 | French OpenGrand Slam, best of 5 | clay | 4th round | Del Potro J.M. | 6-4, 6-4, 6-4 | 6 v 10 |
| Mar 30, 2018 | Sony Ericsson OpenMasters 1000 | hard | semifinal | Isner J. | 6-1, 7-6 | 6 v 17 |
| Nov 3, 2017 | BNP Paribas MastersMasters 1000 | hard | quarterfinal | Isner J. | 6-4, 6-7, 6-4 | 17 v 14 |
| Aug 7, 2017 | Rogers MastersMasters 1000 | hard | 1st round | Del Potro J.M. | 7-5, 7-5 | 31 v 19 |
| Oct 19, 2016 | Stockholm OpenATP250 | hard | 1st round | Del Potro J.M. | 6-4, 7-6 | 63 v 27 |
| Jun 15, 2016 | AEGON ChampionshipsATP500 | grass | 1st round | Isner J. | 7-6, 6-4 | 166 v 17 |
| Aug 17, 2013 | Western & Southern Financial Group MastersMasters 1000 | hard | semifinal | Isner J. | 6-7, 7-6, 6-3 | 7 v 22 |
| Aug 4, 2013 | Citi OpenATP500 | hard | final | Del Potro J.M. | 3-6, 6-1, 6-2 | 7 v 20 |
A record, never a share of meetings. Main-draw singles since 2013; a meeting ended by retirement is counted with the sets that were played and marked; a walkover is listed and counted in neither column. Del Potro J.M. and Isner J. each carry the table against every opponent faced.